0143: Serum thiolactonase activity and paraoxonase gene polymorphism in coronary artery Tunisian patients with or without diabetes
نویسندگان
چکیده
منابع مشابه
Diminished serum paraoxonase activity in patients with coronary artery calcification.
BACKGROUND Previous studies have shown an association between paraoxonase (PON) activity and the presence and severity of coronary atherosclerosis. AIM To demonstrate any association between serum PON activity and the presence and severity of coronary artery calcification (CAC). METHODS A total of 156 consecutive patients having the suspicion of coronary atherosclerosis or needing risk stra...
متن کاملSmoking is associated with reduced serum paraoxonase activity and concentration in patients with coronary artery disease.
BACKGROUND Paraoxonase is an HDL-associated enzyme that protects lipoproteins from oxidative modifications. Smoking is a major cardiovascular risk factor that promotes lipid peroxidation. Cigarette smoke has been shown in vitro to inhibit paraoxonase. The present study examined the hypothesis that smoking is associated with modulated serum activities and concentrations of paraoxonase. METHODS...
متن کاملApolipoprotein E Gene Polymorphism in Iranian Coronary Atherosclerosis Patients Candidate for Coronary Artery Bypass Graft
Objective(s): Apolipoprotein E genotype (APOE) polymorphism affects lipid levels and coronary artery disease (CAD) risk. The aim of this study was to study the association of the Apolipoprotein E genotypes with coronary artery disease in the Iranian population. Materials and Methods: The Apolipoprotein E genotype in DNA samples extracted from 66 CAD+ patients and 61 control s...
متن کاملHsp70-2 gene polymorphism: susceptibility implication in Tunisian patients with coronary artery disease
UNLABELLED Coronary artery disease (CAD) is a multifactorial disease where genetic and environmental factors interact in complex ways to cause the disease. Heat shock protein genes are involved in the progress of CAD. This implies that genetic variants of Hsp70-2 genes might contribute to the development of the CAD. AIM OF STUDY The aim of this study was to characterize statistical correlatio...
متن کاملAssociation of serum paraoxonase activity and coronary artery calcification.
AIM It has been known that there was a relation between the activities of serum paraoxonase (PON) and the severity of the coronary artery disease. However, little is known about association of coronary artery calcification (CAC) and serum PON activities. The aim of this study is to evaluate the relationship between CAC and serum PON activities. PATIENTS AND METHODS We measure serum PON activi...
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ژورنال
عنوان ژورنال: Archives of Cardiovascular Diseases Supplements
سال: 2015
ISSN: 1878-6480
DOI: 10.1016/s1878-6480(15)71726-x